Monday, July 08, 2019

Effect of mobile phone radiation on pentylenetetrazole-induced seizure threshold in mice

. 2016 Jul; 19(7): 800–803

Introduction

The application of mobile phone technology and scientific interest in its potential impact on human brain and performance has significantly increased in the recent years (). Epilepsy is the most common brain disorder after stroke, and its prevalence is growing due to various reasons (). Epilepsy is commonly associated with the brain dysfunctions leading to hyperexcitability of neurons. It is assumed that there is an imbalance between inhibitory GABA-mediated and excitatory glutamate-mediated neurotransmission (). Several studies have demons-
trated the effects of electromagnetic mobile phone waves on central nervous system (). It was shown that brain changes caused by electromagnetic waves are well reflected in the EEG of rats; also the largest changes are reported in brain activity of the limbic and olfactory cortex and the subcortical parts (). It was also demonstrated that if the electromagnetic fields (EMFs) are exactly radiated in the contralateral brain cortex, the patient’s cortex nerve stimulation increases (). A few studies investigated the effects of exposure to EMFs on epileptic disorders in human and experimental subjects, but the results are controversial (). The present study was designed to examine the effects of acute and chronic mobile phone radiation on clonic and tonic seizure thresholds induced by intravenous infusion of pentylenetetrazole (PTZ) in mice.

Conclusion:
Our data suggests that the continued and prolonged contact with the mobile phone radiation might increase the risk of seizure attacks and should be limited.

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