Monday, December 28, 2015

The implications of non-linear biological oscillations on human electrophysiology for electrohypersensitivity (EHS) and multiple chemical sensitivity (MCS)

Rev Environ Health 2015; 30(4): 293–303
Cindy Sage*

The implications of non-linear biologicaloscillations on human electrophysiology forelectrohypersensitivity (EHS) and multiplechemical sensitivity (MCS)

DOI 10.1515/reveh-2015-0007
Received May 6, 2015; accepted July 30, 2015; previously published
online September 12, 2015

Abstract: The ‘informational content’ of Earth's electromagnetic
signaling is like a set of operating instructions
for human life. These environmental cues are dynamic
and involve exquisitely low inputs (intensities) of critical
frequencies with which all life on Earth evolved. Circadian
and other temporal biological rhythms depend on these
fluctuating electromagnetic inputs to direct gene expression,
cell communication and metabolism, neural development,
brainwave activity, neural synchrony, a diversity
of immune functions, sleep and wake cycles, behavior and
cognition. Oscillation is also a universal phenomenon, and
biological systems of the heart, brain and gut are dependent
on the cooperative actions of cells that function according
to principles of non-linear, coupled biological oscillations
for their synchrony. They are dependent on exquisitely
timed cues from the environment at vanishingly small
levels. Altered ‘informational content’ of environmental
cues can swamp natural electromagnetic cues and result
in dysregulation of normal biological rhythms that direct
growth, development, metabolism and repair mechanisms.
Pulsed electromagnetic fields (PEMF) and radiofrequency
radiation (RFR) can have the devastating biological effects
of disrupting homeostasis and desynchronizing normal
biological rhythms that maintain health. Non-linear, weak
field biological oscillations govern body electrophysiology,
organize cell and tissue functions and maintain organ
systems. Artificial bioelectrical interference can give false
information (disruptive signaling) sufficient to affect critical
pacemaker cells (of the heart, gut and brain) and desynchronize
functions of these important cells that orchestrate
function and maintain health. Chronic physiological stress
undermines homeostasis whether it is chemically induced
or electromagnetically induced (or both exposures are
simultaneous contributors). This can eventually break
down adaptive biological responses critical to health maintenance;
and resilience can be compromised. Electrohypersensitivity
can be caused by successive assaults on human
bioelectrochemical dynamics from exogenous electromagnetic
fields (EMF) and RFR or a single acute exposure. Once
sensitized, further exposures are widely reported to cause
reactivity to lower and lower intensities of EMF/RFR, at
which point thousand-fold lower levels can cause adverse
health impacts to the electrosensitive person. Electrohypersensitivity
(EHS) can be a precursor to, or linked with,
multiple chemical sensitivity (MCS) based on reports of
individuals who first develop one condition, then rapidly
develop the other. Similarity of chemical biomarkers is seen
in both conditions [histamines, markers of oxidative stress,
auto-antibodies, heat shock protein (HSP), melatonin
markers and leakage of the blood-brain barrier]. Low intensity
pulsed microwave activation of voltage-gated calcium
channels (VGCCs) is postulated as a mechanism of action
for non-thermal health effects.

*Corresponding author: Cindy Sage, MA, Sage Associates,
1396 Danielson Road, Santa Barbara, CA, 93108 USA,
Phone: +805 969-0557, E-mail:

André Fauteux, Editor/Publisher
La Maison du 21e siècle Magazine 

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