Effect of whole-body exposure to the 848.5-MHz code division multiple access (CDMA) electromagnetic field on adult neurogenesis in the young, healthy rat brain
Kim HS, Kim YJ, Lee YH, Lee YS, Choi HD, Pack JK, Kim N, Ahn YH. Effect of whole-body exposure to the 848.5-MHz code division multiple access (CDMA) electromagnetic field on adult neurogenesis in the young, healthy rat brain. Int J Radiat Biol. 2014 Dec 15:1-15. [Epub ahead of print]
Abstract
Introduction: Whether exposure to the 848.5-MHz code division multiple access (CDMA) signal affects adult neurogenesis is unclear.
Materials and methods: An animal experiment was performed with a reverberation chamber designed as a whole-body CDMA exposure system. Male Sprague-Dawley rats were assigned to three groups (n = 6 per group): cage-control, sham-exposed, and CDMA-exposed groups. Rats in the CDMA-exposed group were exposed to the CDMA signal at a 2 W/kg whole-body specific absorption rate (SAR) for 1 or 8 h daily, 5 days per week, for 2 weeks. Rats received a single intraperitoneal injection of Bromodeoxyuridine (BrdU) to label proliferative cells daily for the last five consecutive days of CDMA signal exposure. An unbiased stereological method was used to estimate the number of BrdU+ cells in the subventricular zone (SVZ) and dentate gyrus (DG).
Results: We found no significant changes in the number of BrdU+ cells in the SVZ or DG in the CDMA-exposed rats, compared with rats in the cage-control and sham-exposed groups (p > 0.05).
Conclusion: Our results suggest that exposure to the CDMA signal does not affect neurogenesis in the adult rat brain, at least under our experimental conditions.
Materials and methods: An animal experiment was performed with a reverberation chamber designed as a whole-body CDMA exposure system. Male Sprague-Dawley rats were assigned to three groups (n = 6 per group): cage-control, sham-exposed, and CDMA-exposed groups. Rats in the CDMA-exposed group were exposed to the CDMA signal at a 2 W/kg whole-body specific absorption rate (SAR) for 1 or 8 h daily, 5 days per week, for 2 weeks. Rats received a single intraperitoneal injection of Bromodeoxyuridine (BrdU) to label proliferative cells daily for the last five consecutive days of CDMA signal exposure. An unbiased stereological method was used to estimate the number of BrdU+ cells in the subventricular zone (SVZ) and dentate gyrus (DG).
Results: We found no significant changes in the number of BrdU+ cells in the SVZ or DG in the CDMA-exposed rats, compared with rats in the cage-control and sham-exposed groups (p > 0.05).
Conclusion: Our results suggest that exposure to the CDMA signal does not affect neurogenesis in the adult rat brain, at least under our experimental conditions.
The absence of bio-effects may also be due to the type of cell phone radiation tested in this study. Prior research on CDMA cell phone radiation has been less like likely to obtain significant bio-effects as compared to research on GSM and UMTS cell phone radiation. I'm only aware of one study of LTE. This study found altered brain functioning in humans after a 30-minute exposure.
--
Joel M. Moskowitz, Ph.D., Director
Center for Family and Community Health
School of Public Health
University of California, Berkeley
Electromagnetic Radiation Safety
Website: http://www.saferemr.com
Facebook: http://www.facebook.com/SaferE
News Releases: http://pressroom.prlog.org/
Twitter: @berkeleyprc
No comments:
Post a Comment