Rev Environ Health 2015; 30(4): 305–309
Gérard Ledoigt*, Chaima Sta, Eric Goujon, Dalila Souguir and Ezzeddine El Ferjani
Synergistic health effects between chemical pollutants and electromagnetic fields
DOI 10.1515/reveh-2015-0028
Received September 11, 2015; accepted November 2, 2015; previously
published online November 24, 2015
Abstract: Humans and ecosystems are exposed to highly
variable and unknown cocktail of chemicals and radiations.
Although individual chemicals are typically present
at low concentrations, they can interact with each other
resulting in additive or potentially synergistic mixture
effects. This was also observed with products obtained
by radiation actions such as sunlight or electromagnetic
fields that can change the effects of chemicals, such as pesticides,
and metal trace elements on health. Concomitant
presence of various pesticides and their transformation
products adds further complexity to chemical risk assessment
since chronic inflammation is a key step for cancer
promotion. Degradation of a parent molecule can produce
several by-products which can trigger various toxic
effects with different impacts on health and environment.
For instance, the cocktail of sunlight irradiated sulcotrione
pesticide has a greater cytotoxicity and genotoxicity
than parent molecule, sulcotrione, and questions about
the impact of photochemical process on environment.
Adjuvants were shown to modify the biological features of
pesticides. Addition of other elements, metals or biological
products, can differently enhance cell toxicity of pesticides
or electromagnetic radiations suggesting a synergy
in living organisms. Electromagnetic fields spreading,
pesticide by-products and mixtures monitoring become
greater for environmental contamination evaluations.
*Corresponding author: Pr. Gérard Ledoigt, Clermont Université,
Université Blaise Pascal, Campus Universitaire des Cézeaux,
UMR 547 PIAF, B.P. 10448, F-63000 Clermont-Ferrand, France,
Phone: +33 473407908, Fax: +33 473407951,
Chaima Sta: Clermont Université, Université Blaise Pascal, Campus
Universitaire des Cézeaux, UMR 547 PIAF, B.P. 10448, F-63000
Clermont-Ferrand, France; and Laboratoire de Physiologie et
GeÅLneÅLtique des Plantes aÅL InteÅLreÅLt Agronomique, FaculteÅL des Sciences
de Bizerte, UniversiteÅL de Carthage, 7021 Jarzouna, Tunisie
Eric Goujon: Clermont Université, Université Blaise Pascal, Campus
Universitaire des Cézeaux, UMR 547 PIAF, B.P. 10448, F-63000
Clermont-Ferrand, France
Dalila Souguir: Institut National de Recherches en Génie Rural, Eaux
et Forêts, Rue HeÅLdi Karray El Manzah IV, BP-10-Ariana 2080- Tunisie
Ezzeddine El Ferjani: Laboratoire de Physiologie et Génétique des
Plantes à intérêt agronomique, Faculté des Sciences de Bizerte,
Université de Carthage, 7021 Jarzouna, Tunisie
—
André Fauteux, Editor/Publisher
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