Le 2015-04-27 à 14:37, Evelyn Savarin a écrit :
Andre,
Came across this Study and felt important to pass on. Although
study was performed using 50 HZ fields It confirms the importance of Waveform
even more than Dosage in adverse EMF Studies. Could help explain Negative
or Non- adverse effect EMF - RF studies, as well as beneficial effects EMF
studies.
Evelyn Savarin
Bioelectromagnetics. 2014 Jan;35(1):30-8.
doi: 10.1002/bem.21794. Epub 2013 Jun 17.
Different electromagnetic field waveforms have different effects on proliferation, differentiation and mineralization of osteoblasts in vitro.
Abstract
Noninvasive electromagnetic fields (EMFs) have been known to be
able to improve bone health; however, their optimal application parameters and
action mechanisms remain unclear. This study compared the effects of different
forms of EMFs (sinusoidal, triangular, square, and serrated, all set at 50 Hz frequency and 1.8 mT intensity) on
proliferation, differentiation and mineralization of rat calvarial osteoblasts.
Square EMFs stimulated osteoblast proliferation but sinusoidal EMFs inhibited
it. Sinusoidal and triangular EMFs produced significantly greater alkaline
phosphatase (ALP) activity, ALP staining areas, calcium deposition, mineralized
nodule areas, and mRNA expression of Runx-2, osteoprotegerin and insulin-like
growth factor-I than square and serrated EMFs (P < 0.01). Triangular EMFs had a greater effect than sinusoidal EMFs
on every indices except for Runx-2 mRNA expression (P < 0.05). These results indicated that
while square EMFs promoted proliferation and had no effect on the
differentiation of osteoblasts, sinusoidal EMFs inhibited proliferation but
enhanced osteogenic differentiation. Triangular EMFs did not affect cell
proliferation but induced the strongest osteogenic activity among the four
waveforms of EMFs. Thus, the effects of EMFs on proliferation and
differentiation of osteoblasts in vitro were dependent on their waveforms.
Copyright © 2013 Wiley Periodicals, Inc.
Thanks, Evelyn
--
Andre Fauteux, Editor
La Maison du 21e siècle magazine
2955 Domaine-lac-Lucerne
Ste-Adèle (Qc)
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