Wednesday, April 15, 2015

Long-term use of mobile phone and its association with glioma: a systematic review and meta-analysis [Article in Chinese]

Joel's comments: Although the authors of this review paper which was written in Chinese argued that the evidence for cancer risk is insufficient, they reported a significant overall 1.5-fold increased risk of glioma after long-term cell phone use and a significant 2.3 fold risk for low-grade glioma on the side of the head where people predominantly used their phones.

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Long-term use of mobile phone and its association with glioma: a systematic review and meta-analysis [Article in Chinese]
Abstract


Abstract


Gong X, Wu J, Mao Y, Zhou L, [Long-term use of mobile phone and its association with glioma: a systematic review and meta-analysis]. Zhonghua Yi Xue Za Zhi. 2014 Oct 28;94(39):3102-6.

Abstract

OBJECTIVE: The hypothesis that "cell phone induces brain tumor" has become a target of much controversy for several decades and is still a matter of debate even now. We aim to make a systematic review and meta-analysis based on published studies on glioma to identify current evidences for evaluating mobile phones and glioma risk, especially on long-term use of mobile phones.

METHODS: The study was conducted according to the Cochrane systematic review methods and reported according to the PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) statement according to a prospective research protocol accessed via http://www.crd.york.ac.uk/prospero. The software RevMan 5 was used for statistic analysis. Latency and lateralization were used for the examining the dose-response relationship.

RESULTS: Overall evidence suggested the increased risk of glioma among long-term ipsilateral users of mobile phone with an odds ratio (OR) of 1.46 [1.12, 1.92] based on meta-analysis. Especially, for low-grade glioma, long-term use yielded an OR value of 2.27 [1.81, 2.85].

CONCLUSION: The evidence is currently insufficient on this issue, especially on long-term use of mobile phone. Neither a definite answer nor a clear explanation may be offered for the relationship. And larger prospective trials are warranted.

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Joel M. Moskowitz, Ph.D., Director
Center for Family and Community Health
School of Public Health
University of California, Berkeley

Electromagnetic Radiation Safety

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